Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50000414
TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50343500((R)-N-(4-(4-(4-fluorophenyl)-1-methyl-2-(methylsul...)
Affinity DataIC50: 129nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by beta-galactosidase enzyme complementation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 700nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 710nMAssay Description:Inhibition of P38 MAPKalpha in LPS-stimulated human whole blood assessed as decrease in TNFalpha levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 710nMAssay Description:Inhibition of P38 MAPKalpha in LPS-stimulated human whole blood assessed as decrease in TNFalpha levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 800nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human PDE4B1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human PDE4D3 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50238154(CHEMBL321494)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human PDE4A4 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human PDE4B1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human PDE4C1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human PDE4A4 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDE4C1 expressed in sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50130648(N-{4-[5-(4-Fluoro-phenyl)-3-methyl-2-methylsulfany...)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249599(CHEMBL4075428)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
C-A-I-R Biosciences

Curated by ChEMBL
LigandPNGBDBM50249598(CHEMBL1773422)
Affinity DataIC50: 2.13E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed