Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50001034
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM17989(N-{2-[6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50330347(6-(2,4-diamino-6-ethyl-pyrimidin-5-yl)-2-(3,5-difl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM17983(diaminopyrimidine renin inhibitor compound, 6 | N-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268115(CHEMBL4080664)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM18011((2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268089(CHEMBL4075401)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268114(CHEMBL4098706)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268120(CHEMBL4083180)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268117(CHEMBL4088533)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM18010(6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-diflu...)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM17983(diaminopyrimidine renin inhibitor compound, 6 | N-...)
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268122(CHEMBL4061317)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268088(CHEMBL4092429)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268116(CHEMBL4075327)
Affinity DataIC50: 267nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268119(CHEMBL4088532)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268112(CHEMBL4078887)
Affinity DataIC50: 491nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268090(CHEMBL4102221)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM18037(6-ethyl-5-[1-(3-methoxypropyl)-1,2,3,4-tetrahydroq...)
Affinity DataIC50: 512nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268087(CHEMBL4071636)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268123(CHEMBL4090971)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268095(CHEMBL4068297)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268118(CHEMBL4100169)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM18036(5-(4-{[(3,5-difluorophenyl)methyl]amino}phenyl)-6-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human renin expressed in CHOK1 cells by fluorescence GTP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268096(CHEMBL4101134)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268099(CHEMBL4082168)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268098(CHEMBL4074387)
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268094(CHEMBL4075644)
Affinity DataIC50: 8.53E+3nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268093(CHEMBL4072875)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268111(CHEMBL4096917)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268091(CHEMBL4094484)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268113(CHEMBL4077961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetRenin(Human)
Bioleap

Curated by ChEMBL
LigandPNGBDBM50268092(CHEMBL4093580)
Affinity DataIC50: 1.24E+5nMAssay Description:Inhibition of recombinant human renin using 5-FAM/QXL 520 as substrate pretreated for 30 mins followed by substrate addition measured at 1 min interv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed