Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50000053
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 5nMAssay Description:Inhibition of human N-terminal GST/His6-tagged GSK3beta (M1 to T420 residues) expressed in baculovirus infected sf9 cells using RBER-IRStide as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239780(CHEMBL4065365)
Affinity DataIC50: 43nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239778(CHEMBL1830064)
Affinity DataIC50: 54nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 75nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239778(CHEMBL1830064)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 90nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239778(CHEMBL1830064)
Affinity DataIC50: 160nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239774(CHEMBL4084775)
Affinity DataIC50: 169nMAssay Description:Inhibition of IGF1R (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 210nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239778(CHEMBL1830064)
Affinity DataIC50: 210nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239779(CHEMBL1802727)
Affinity DataIC50: 230nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239777(CHEMBL4100748)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/Cyclin B1 (M1 to V433 residues) expressed in sf9 cells using RB...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 410nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239773(CHEMBL492244)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK5 (M1 to P292 residues)/p35NCK (M1 to R307 residues) expressed in baculovirus infected sf9 c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 540nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 620nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239775(CHEMBL4100916)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) after 10 mins in presence of [gamma32P]ATP by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 840nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239778(CHEMBL1830064)
Affinity DataIC50: 910nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239777(CHEMBL4100748)
Affinity DataIC50: 920nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239775(CHEMBL4100916)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50005337(CHEMBL1276317)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239777(CHEMBL4100748)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239775(CHEMBL4100916)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CDK2/CyclinE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 3.49E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of IGF1R (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CDK5/p35NCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239776(CHEMBL4085289)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CDK2/CyclinA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 7.89E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239777(CHEMBL4100748)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinA expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human N-terminal His6-tagged CDK6/N-terminal GST-tagged CyclinD3 expressed in sf21 cells after 10 mins in presence of [gamm...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239777(CHEMBL4100748)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM50239775(CHEMBL4100916)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) expressed in starfish oocytes using histone h1 as substrate after 10 mins in presence of [gamma32P]ATP b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK1/N-terminal GST-tagged CyclinB expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Kaiserslautern

Curated by ChEMBL
LigandPNGBDBM7392(2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed