Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50000226
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242734(CHEMBL4070331)
Affinity DataIC50: 29nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242736(CHEMBL4098990)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50: 43nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242747(CHEMBL4078790)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242748(CHEMBL4103066)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242750(CHEMBL4080965)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242745(CHEMBL4087613)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP19 using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242754(CHEMBL4095313)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242753(CHEMBL4074186)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242751(CHEMBL1650709)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242749(CHEMBL1430816)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242746(CHEMBL4063099)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242744(CHEMBL4105495)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242743(CHEMBL4100188)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50303499(7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242739(CHEMBL1650711)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242738(CHEMBL4099909)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed
TargetAromatase(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50242735(CHEMBL4091260)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed