Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50000030
LigandPNGBDBM50239399(CHEMBL4069027)
Affinity DataIC50: 1.26nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50239399(CHEMBL4069027)
Affinity DataIC50: 6.31nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 25.1nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50239402(CHEMBL4090825)
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataIC50: 50.1nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50239399(CHEMBL4069027)
Affinity DataKi:  1.58nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50239399(CHEMBL4069027)
Affinity DataKi:  3.16nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataKi:  12.6nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50239400(CHEMBL4080605)
Affinity DataKi:  12.6nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50323726(2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tol...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50239402(CHEMBL4090825)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50239400(CHEMBL4080605)
Affinity DataKi:  125nMAssay Description:Inhibition of human recombinant full length N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 insect cells using P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details Article
PubMed