Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50000210
LigandPNGBDBM50240267(CHEMBL2325014)
Affinity DataIC50: 11nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells measured after 5 to 10 mins post compound washout by PatchXpress automated ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50242510(CHEMBL4095146)
Affinity DataIC50: 11nMAssay Description:Inhibition of 50% inactivated mouse Nav1.7alpha incubated for 5 mins measured at 10 secs interval by PatchXpress automated electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 21nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 29nMAssay Description:Inhibition of Nav1.2 (unknown origin)More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 30nMAssay Description:Inhibition of 50% inactivated mouse Nav1.7alpha incubated for 5 mins measured at 10 secs interval by PatchXpress automated electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 31nMAssay Description:Inhibition of NaV1.7 channel in human DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242510(CHEMBL4095146)
Affinity DataIC50: 39nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242508(CHEMBL4084948)
Affinity DataIC50: 74nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 82nMAssay Description:Inhibition of NaV1.7 channel in mouse DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242504(CHEMBL4090017)
Affinity DataIC50: 134nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242506(CHEMBL4077789)
Affinity DataIC50: 150nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242507(CHEMBL4102898)
Affinity DataIC50: 190nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242502(CHEMBL4082170)
Affinity DataIC50: 486nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242505(CHEMBL4102052)
Affinity DataIC50: 535nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242501(CHEMBL4060266)
Affinity DataIC50: 815nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242511(CHEMBL4071639)
Affinity DataIC50: 970nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242509(CHEMBL4068937)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of NaV1.7 channel in rat DRG neurons assessed as reduction of TTX-sensitive sodium current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242503(CHEMBL4098657)
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50240267(CHEMBL2325014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells measured after 5 to 10 mins post compound washout by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242511(CHEMBL4071639)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242502(CHEMBL4082170)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50242501(CHEMBL4060266)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed