Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50000019
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239258(CHEMBL4070727)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239257(CHEMBL4071777)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239256(CHEMBL4082283)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239266(CHEMBL4092561)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239265(CHEMBL4073410)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239259(CHEMBL4097849)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239260(CHEMBL4090131)
Affinity DataIC50: 5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239261(CHEMBL4065901)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239263(CHEMBL4063778)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239269(CHEMBL4101799)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239262(CHEMBL4091576)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239264(CHEMBL4083794)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239255(CHEMBL4076289)
Affinity DataIC50: 14nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239268(CHEMBL4093508)
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239254(CHEMBL4070322)
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239267(CHEMBL4062100)
Affinity DataIC50: 31nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239258(CHEMBL4070727)
Affinity DataIC50: 235nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 265nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 392nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239255(CHEMBL4076289)
Affinity DataIC50: 453nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 629nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239254(CHEMBL4070322)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Haisco Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50239256(CHEMBL4082283)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2019
Entry Details Article
PubMed