Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50000503
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50244142(CHEMBL4086356 | US10533010, Example I-240 | US1120...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50244142(CHEMBL4086356 | US10533010, Example I-240 | US1120...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50244142(CHEMBL4086356 | US10533010, Example I-240 | US1120...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50244142(CHEMBL4086356 | US10533010, Example I-240 | US1120...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of BSA by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251649(CHEMBL4064457)
Affinity DataKi:  20nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251650(CHEMBL4099902)
Affinity DataKi:  22nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251649(CHEMBL4064457)
Affinity DataKi:  32nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251669(CHEMBL4073037)
Affinity DataKi:  48nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251650(CHEMBL4099902)
Affinity DataKi:  73nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50251669(CHEMBL4073037)
Affinity DataKi:  262nMAssay Description:Inhibition of FITC-Bak-BH3 binding to recombinant MBP-fused MCL1 (172 to 318 residues) (unknown origin) in presence of 1% FBS by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed