Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50000381
Affinity DataEC50: >3.10E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cell membranes after 45 mins by [35S] GTPgammaS binding based scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cell membranes after 45 mins by [35S] GTPgammaS binding based scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cell membranes after 45 mins by [35S] GTPgammaS binding based scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cell membranes after 45 mins by [35S] GTPgammaS binding based scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at S1P1 receptor (unknown origin) expressed in CHO cell membranes after 60 mins by [35S] GTPgammaS binding based scintillation count...More data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Agonist activity at human S1P1 receptor expressed in cell membranes after 30 mins by [35S] GTPgammaS binding based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO cell membranes after 45 mins by [35S] GTPgammaS binding based scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [33P]-S1P from S1P1 receptor (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [33P]-S1P from S1P3 receptor (unknown origin) expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human ATX using FS-3 as substrate incubated for 30 mins followed by substrate addition measured for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranes after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [33P]-S1P from S1P1 receptor (unknown origin) expressed in CHOK1 cells after 60 mins by microbeta scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [33P]-S1P from S1P1 receptor (unknown origin) expressed in CHOK1 cells after 60 mins by microbeta scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Displacement of [33P]-S1P from S1P3 receptor (unknown origin) expressed in CHOK1 cells after 60 mins by microbeta scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [33P]-S1P from S1P3 receptor (unknown origin) expressed in CHOK1 cells after 60 mins by microbeta scintillation proximity assayMore data for this Ligand-Target Pair
