Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50049167
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 31.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235580(CHEMBL4092150)
Affinity DataIC50: 56.3nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235579(CHEMBL4073025)
Affinity DataIC50: 72.4nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235583(CHEMBL4100781)
Affinity DataIC50: 97.4nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18512(cid_4993 | CHEMBL36 | 5-(4-chlorophenyl)-6-ethylpy...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 144nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235582(CHEMBL4102361)
Affinity DataIC50: 160nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
Affiliated To Sardar Patel University

Curated by ChEMBL
LigandPNGBDBM50235581(CHEMBL4064442)
Affinity DataIC50: 168nMAssay Description:Inhibition of bovine liver DHFR using FH2 as substrate preincubated for 2 mins followed by substrate addition in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details Article
PubMed