Compile Data Set for Download or QSAR
Report error Found 111 Enz. Inhib. hit(s) with all data for entry = 50049218
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236832(CHEMBL4093699)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236836(CHEMBL4073586)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236812(CHEMBL4070284)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236844(CHEMBL4100484)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236756(CHEMBL4101284)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236756(CHEMBL4101284)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236847(CHEMBL4085003)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236832(CHEMBL4093699)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236812(CHEMBL4070284)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236847(CHEMBL4085003)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236833(CHEMBL4062687)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236833(CHEMBL4062687)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236836(CHEMBL4073586)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236844(CHEMBL4100484)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50318633(SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...)
Affinity DataKi:  0.230nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(LU-AE58054 | IDALOPIRDINE)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236846(CHEMBL4080401)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50044616(Cerlapirdine | PF-05212365 | SAM-531 | WAY-262531)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236844(CHEMBL4100484)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236780(CHEMBL4068232)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236756(CHEMBL4101284)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236773(CHEMBL4065437)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236832(CHEMBL4093699)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236806(CHEMBL4100411)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236831(CHEMBL4077537)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236836(CHEMBL4073586)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236792(CHEMBL4083289)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236843(CHEMBL4105377)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236833(CHEMBL4062687)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236777(CHEMBL4097459)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236821(CHEMBL4075502)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236834(CHEMBL4073450)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236803(CHEMBL4095054)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236801(CHEMBL4092681)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236839(CHEMBL4083893)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236810(CHEMBL4103281)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236812(CHEMBL4070284)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236793(CHEMBL4064478)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236788(CHEMBL4085949)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2019
Entry Details Article
PubMed
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