Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with all data for entry = 50049205
LigandPNGBDBM50236511(CHEMBL3718319)
Affinity DataKd:  6nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236534(CHEMBL4091855)
Affinity DataKon:  0.290M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236513(CHEMBL3715902)
Affinity DataKd:  9nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKd:  19nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236515(CHEMBL3717621)
Affinity DataKd:  10nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236516(CHEMBL3731789)
Affinity DataKd:  1nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236517(CHEMBL3732579)
Affinity DataKd:  10nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236518(CHEMBL3732469)
Affinity DataKd:  16nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236519(CHEMBL3727843)
Affinity DataKd:  78nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236520(CHEMBL3717438)
Affinity DataKd:  10nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50177026(CHEMBL3814630)
Affinity DataKd:  4.08E+4nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236523(CHEMBL3714988)
Affinity DataKon:  0.230M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236512(CHEMBL3716663)
Affinity DataKd:  153nMAssay Description:Binding affinity to PDHK1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236518(CHEMBL3732469)
Affinity DataKd:  60nMAssay Description:Binding affinity to PDHK1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236524(CHEMBL3718004)
Affinity DataKon:  0.600M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236521(CHEMBL3715843)
Affinity DataKon:  0.0800M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM265209(US9718793, 41j | US10413550, Example 41j | US11234...)
Affinity DataKon:  0.00100M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236523(CHEMBL3714988)
Affinity DataKon:  0.0800M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKd:  19nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236529(CHEMBL3730154)
Affinity DataKon:  0.140M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236524(CHEMBL3718004)
Affinity DataKon:  0.270M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236512(CHEMBL3716663)
Affinity DataKd:  153nMAssay Description:Binding affinity to PDHK1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236534(CHEMBL4091855)
Affinity DataKon:  0.0190M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataKd:  150nMAssay Description:Binding affinity to PDHK1 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236529(CHEMBL3730154)
Affinity DataKon:  0.260M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM265209(US9718793, 41j | US10413550, Example 41j | US11234...)
Affinity DataKon:  0.0140M-1s-1Assay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236521(CHEMBL3715843)
Affinity DataKon:  0.180M-1s-1Assay Description:Binding affinity to HSP90A (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236520(CHEMBL3717438)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 35nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236511(CHEMBL3718319)
Affinity DataIC50: 36nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDHK3 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataIC50: 41nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236516(CHEMBL3731789)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataIC50: 63nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236533(CHEMBL316388)
Affinity DataIC50: 66nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236518(CHEMBL3732469)
Affinity DataIC50: 72nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 84nMAssay Description:Inhibition of PDHK2 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 91nMAssay Description:Inhibition of PDHK4 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236519(CHEMBL3727843)
Affinity DataIC50: 101nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236513(CHEMBL3715902)
Affinity DataIC50: 135nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236512(CHEMBL3716663)
Affinity DataIC50: 139nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236515(CHEMBL3717621)
Affinity DataIC50: 198nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236517(CHEMBL3732579)
Affinity DataIC50: 201nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236526(CHEMBL4089806)
Affinity DataIC50: 350nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK2 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236530(CHEMBL3727577)
Affinity DataIC50: 573nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM227594(PS10)
Affinity DataIC50: 800nMAssay Description:Inhibition of PDHK2 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM227594(PS10)
Affinity DataIC50: 840nMAssay Description:Inhibition of PDHK4 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236518(CHEMBL3732469)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236513(CHEMBL3715902)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM227594(PS10)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
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