Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50048292
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 82nMAssay Description:Inhibition of full length human His6/GST-tagged NQO2 expressed in Escherichia coli Tuner(DE3)pLysS using menadione as substrate and CCHP as co-substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 381nMAssay Description:Inhibition of full length human His6/GST-tagged NQO2 expressed in Escherichia coli Tuner(DE3)pLysS using menadione as substrate and CCHP as co-substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetPyridoxal kinase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged PDXK expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetPyridoxal kinase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of fluorescein-labeled ML349 binding to HEK293T cells-derived His-tagged PDXK expressed in Escherichia coli BL21(DE3) after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM207992(ML349)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50212216(CHEMBL3944678)
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50212217(CHEMBL3917640)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50212218(CHEMBL3974081)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed