Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50048997
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50: 800nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232634(CHEBI:67726 | Furospongin 1)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed