Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50000920
TargetIntegrin alpha-IIb/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264380(CHEMBL4078717)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in human platelet-rich plasma assessed as inhibition of ADP-induced platelets aggregation by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50124573(CHEMBL1472460)
Affinity DataIC50: 95nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in citrated human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264414(CHEMBL4094316)
Affinity DataIC50: 466nMAssay Description:Inhibition of biotin-fibronectin binding to human placental ruthenium-labelled BV-tagged alpha5beta1 integrin measured after 6 hrs by electrochemilum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264414(CHEMBL4094316)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of alpha5 beta1 integrin (unknown origin)-mediated human K562 cell adhesion to GST-tagged fibronectin after 45 mins by crystal violet stai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50124572(CHEMBL1234739)
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in citrated human platelet-rich plasma assessed as inhibition of ADP-induced platelets aggrega...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrin alpha-IIb/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at integrin alpha2b beta3 receptor in citrated human platelet-rich plasma assessed as inhibition of ADP-induced platelet aggregat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264413(CHEMBL4073710)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of alpha5 beta1 integrin (unknown origin) by cell migration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264413(CHEMBL4073710)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of alpha5 beta1 integrin (unknown origin) by cell proliferation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50264380(CHEMBL4078717)
Affinity DataKi: <1nMAssay Description:Displacement of [3H]UR-3189 from integrin alpha2b beta3 receptor in resting human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)