Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50048291
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM74255(SMR001261423 | 1,3-Benzenediamine, 2-methyl- | 2-m...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM26188(1,2-Dihydroxybenzene, XI | CHEMBL280998 | benzene-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of full length PI3Kalpha (unknown origin) assessed as reduction in PIP3 formation using PIP2 as substrate after 45 mins by fluorescence po...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)