Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with all data for entry = 50000990
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267009(CHEMBL4089171)
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267010(CHEMBL4082395)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244066(CHEMBL4083365)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR40 transfected in HEK293 cells assessed as induction of cAMP accumulation incubated for 30 to 45 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267011(CHEMBL4084441)
Affinity DataEC50:  6.50E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267012(CHEMBL4100898)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267013(CHEMBL4074138)
Affinity DataEC50:  680nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267017(CHEMBL4093180)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267018(CHEMBL4065518)
Affinity DataEC50:  490nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267019(CHEMBL4085420)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267020(CHEMBL4103345)
Affinity DataEC50:  520nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267021(CHEMBL4091669)
Affinity DataEC50: >1.70E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267022(CHEMBL4072491)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267026(CHEMBL4099410)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267027(CHEMBL4094160)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267117(CHEMBL4060499)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267029(CHEMBL4069191)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267030(CHEMBL4090240)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267119(CHEMBL1532576)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267034(CHEMBL4098892)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267035(CHEMBL4071899)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267111(CHEMBL4063536)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267037(CHEMBL4082975)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267119(CHEMBL1532576)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267039(CHEMBL4090766)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267044(CHEMBL4069764)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267045(CHEMBL4063889)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267046(CHEMBL4103729)
Affinity DataEC50:  1.70E+4nMAssay Description:Transactivation of human Gal4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267047(CHEMBL4078852)
Affinity DataEC50:  3.20E+4nMAssay Description:Transactivation of human Gal4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244066(CHEMBL4083365)
Affinity DataEC50:  4.40E+3nMAssay Description:Transactivation of human Gal4 fused PPARgamma-LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267048(CHEMBL4075190)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267061(CHEMBL4060859)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267050(CHEMBL4097951)
Affinity DataEC50:  82nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267010(CHEMBL4082395)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244066(CHEMBL4083365)
Affinity DataEC50:  54nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267051(CHEMBL4101348)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267052(CHEMBL4082459)
Affinity DataEC50:  53nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267054(CHEMBL4062765)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267017(CHEMBL4093180)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267018(CHEMBL4065518)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267019(CHEMBL4085420)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267020(CHEMBL4103345)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267048(CHEMBL4075190)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267049(CHEMBL4095599)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267037(CHEMBL4082975)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267038(CHEMBL4061093)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267117(CHEMBL4060499)
Affinity DataEC50:  780nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267055(CHEMBL4059947)
Affinity DataEC50: >1.60E+4nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267083(CHEMBL4088190)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at mouse GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267055(CHEMBL4059947)
Affinity DataEC50:  6.40E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267056(CHEMBL4068606)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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