Compile Data Set for Download or QSAR
Report error Found 136 Enz. Inhib. hit(s) with all data for entry = 50006639
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human PC3 cells assessed as decrease in AKT1 phosphorylation at Ser473 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataEC50:  7.30nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human LNCaP cells assessed as decrease in AKT1 phosphorylation at Ser473 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataEC50:  5.70nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-415 cells assessed as decrease in AKT1 phosphorylation at Ser473 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataEC50:  3.40nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human ZR-75-1 cells assessed as decrease in AKT1 phosphorylation at Ser473 after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501405(CHEMBL4074361)
Affinity DataEC50:  4.20nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501410(CHEMBL4101102)
Affinity DataEC50:  7.60nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501413(CHEMBL4079545)
Affinity DataEC50:  45nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataEC50:  20nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501415(CHEMBL4085918)
Affinity DataEC50:  15nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501416(CHEMBL4102306)
Affinity DataEC50:  42nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501408(CHEMBL4081433)
Affinity DataEC50:  3.70nMAssay Description:Inhibition of PI3K p110beta in PTEN-deficient human PC3 cells assessed as decrease in AKT phosphorylation at ser473 after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501402(CHEMBL4071605)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501399(CHEMBL4100135)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50168484(CHEMBL3805137 | US9765060, Compound Y)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501400(CHEMBL4082130)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501403(CHEMBL4084645)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501408(CHEMBL4081433)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501399(CHEMBL4100135)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501402(CHEMBL4071605)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501408(CHEMBL4081433)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501411(CHEMBL4068742)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501403(CHEMBL4084645)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501411(CHEMBL4068742)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501407(CHEMBL4059461)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501405(CHEMBL4074361)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501405(CHEMBL4074361)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501400(CHEMBL4082130)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501415(CHEMBL4085918)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501409(CHEMBL4061937)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501424(CHEMBL4088324)
Affinity DataIC50: 3nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501401(CHEMBL4092381)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501415(CHEMBL4085918)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501416(CHEMBL4102306)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501412(CHEMBL4096052)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501410(CHEMBL4101102)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501412(CHEMBL4096052)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501422(CHEMBL4064384)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501416(CHEMBL4102306)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501398(CHEMBL4082978)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501410(CHEMBL4101102)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501413(CHEMBL4079545)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501421(CHEMBL4100094)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501426(CHEMBL4080464)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501423(CHEMBL4060084)
Affinity DataIC50: 12nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501406(CHEMBL4078045)
Affinity DataIC50: 13nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501413(CHEMBL4079545)
Affinity DataIC50: 13nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501401(CHEMBL4092381)
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human PI3K p110beta/untagged recombinant full length human p85alpha expressed in baculov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501409(CHEMBL4061937)
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
LigandPNGBDBM50501417(CHEMBL4061095)
Affinity DataIC50: 15nMAssay Description:Inhibition of human full length PI3K p110delta/p85 alpha using PIP2/ATP as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
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