Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 7807
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 25nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM50179009(Kuwanon L | CHEMBL377937)
Affinity DataIC50: 570nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM50179009(Kuwanon L | CHEMBL377937)
Affinity DataIC50: 990nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189342(RDS1759)
Affinity DataIC50: 7.40E+3nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM189342(RDS1759)
Affinity DataIC50: 5.00E+4nMpH: 8.1Assay Description:The RNA-dependent DNA polymerase (RDDP) activity associated with HIV-1 RT was measured by use of the Invitrogen EnzCheck Reverse Transcriptase Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Siena

LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 5.00E+4nMpH: 7.8Assay Description:The RNase H activity associated with HIV-1 RT was measured in a 100 mL reactionvolume containing Tris HCl (pH 7.8, 50 mm), MgCl2 (6 mm), dithiothreit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)