Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50048159
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50129964(1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50112086(CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206816(CHEMBL3907547)
Affinity DataIC50: 83nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206818(CHEMBL3969770)
Affinity DataIC50: 147nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206800(CHEMBL3922260)
Affinity DataIC50: 437nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206815(CHEMBL3950003)
Affinity DataIC50: 446nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206809(CHEMBL3913261)
Affinity DataIC50: 456nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206799(CHEMBL3958679)
Affinity DataIC50: 511nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50432209(BIBR-1048 | BIBR-1048-BS-RS1 | Pradaxa | DABIGATRA...)
Affinity DataIC50: 554nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206810(CHEMBL3931186)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206801(CHEMBL3977163)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206803(CHEMBL3964811)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206813(CHEMBL3978841)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206802(CHEMBL3935798)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206798(CHEMBL3960020)
Affinity DataIC50: 8.16E+3nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206808(CHEMBL3909953)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206805(CHEMBL3979276)
Affinity DataIC50: 8.82E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206811(CHEMBL3971094)
Affinity DataIC50: 9.12E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206814(CHEMBL3899919)
Affinity DataIC50: 9.15E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206806(CHEMBL3889895)
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206807(CHEMBL3890936)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206804(CHEMBL3961893)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetThrombin(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206812(CHEMBL3908646)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed