Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50048811
TargetMuscarinic acetylcholine receptor M5(Mouse)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228206(Dexetimide | R-16470 [as hydrochloride])
Affinity DataIC50: 3.30nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556(Dexetimide1'-Benzyl-3-phenyl-[3,4']bipiperidinyl-2...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228211(CHEMBL274789)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228212(CHEMBL10086)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228214(CHEMBL10278)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228209(CHEMBL10399)
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228213(CHEMBL273262)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018560(1'-(4-Chloro-benzyl)-3-phenyl-[3,4']bipiperidinyl-...)
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228205(CHEMBL10331)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018553(CHEMBL10309 | (+/-)-1'-(4-bromobenzyl)-3-phenyl-3,...)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018551(1'-(4-Fluoro-benzyl)-3-phenyl-[3,4']bipiperidinyl-...)
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228207(CHEMBL9966)
Affinity DataIC50: 460nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228208(CHEMBL274552)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Rat)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228210(CHEMBL276237)
Affinity DataIC50: 500nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Mouse)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataIC50: 750nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Mouse)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556(Dexetimide1'-Benzyl-3-phenyl-[3,4']bipiperidinyl-2...)
Affinity DataIC50: 8.90E+3nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Mouse)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 3.50E+4nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to Dopamine receptor of miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to opioid receptor miceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)