Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50048093
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as increase in forskolin-stim...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as increase in forskolin-stim...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu4 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >1.25E+4nMAssay Description:Agonist activity at recombinant human mGlu6 receptor expressed in hamster AV12 cells co-expressing EAAT1 assessed as induction of forskolin-stimulate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu1 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu5 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as increase in Ca2+ ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at recombinant human mGlu8 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as induction of forskolin-sti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204259(CHEMBL3913414)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204268(CHEMBL3977508)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204267(CHEMBL3939492)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204256(CHEMBL3948272)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204267(CHEMBL3939492)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204259(CHEMBL3913414)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204256(CHEMBL3948272)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204258(CHEMBL3933829)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204268(CHEMBL3977508)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204258(CHEMBL3933829)
Affinity DataIC50: 54nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204266(CHEMBL3961306)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204266(CHEMBL3961306)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204253(CHEMBL3956934)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204270(CHEMBL3918170)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204255(CHEMBL3927108)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204264(CHEMBL3890112)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204260(CHEMBL3971347)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204270(CHEMBL3918170)
Affinity DataIC50: 149nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204269(CHEMBL3909237)
Affinity DataIC50: 153nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204269(CHEMBL3909237)
Affinity DataIC50: 169nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204271(CHEMBL3953570)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204263(CHEMBL3979475)
Affinity DataIC50: 185nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204260(CHEMBL3971347)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204255(CHEMBL3927108)
Affinity DataIC50: 215nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204264(CHEMBL3890112)
Affinity DataIC50: 225nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204262(CHEMBL3955458)
Affinity DataIC50: 239nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204271(CHEMBL3953570)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204262(CHEMBL3955458)
Affinity DataIC50: 306nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204253(CHEMBL3956934)
Affinity DataIC50: 312nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204263(CHEMBL3979475)
Affinity DataIC50: 387nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204252(CHEMBL3930511)
Affinity DataIC50: 1.07E+3nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204252(CHEMBL3930511)
Affinity DataIC50: 1.13E+3nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at recombinant human mGlu8 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at recombinant human mGlu6 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as inhibition of L-AP4-inh...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 1.05E+4nMAssay Description:Antagonist activity at recombinant human mGlu7 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu1 receptor expressed in hamster AV12 cells coexpressing human EAAT1/Galpha1s assessed as inhibition of C...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu4 receptor expressed in hamster AV12 cells co-expressing human EAAT1/Galpha1s assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204257(CHEMBL3947221)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu5 receptor expressed in hamster AV12 cells coexpressing human EAAT1/Galpha1s assessed as inhibition of C...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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