Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 7500
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 5.95E+4nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
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PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198131(Ethyl 4-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198132(Ethyl 4-(3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198133(Ethyl 4-(3-(3-bromophenyl)-1-phenyl-1H-pyrazol-4-y...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198134(Ethyl 4-(3-(3-bromophenyl)-1-phenyl-1H-pyrazol-4-y...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198135(Ethyl 4-(3-(3-nitrophenyl)-1-phenyl-1H-pyrazol-4-y...)
Affinity DataIC50: 1.00E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198130(Ethyl 4-(1,3-diphenyl-1H-Pyrazol-4-yl)-2-oxo-6-(py...)
Affinity DataIC50: 2.22E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198139(5-(1,3-Diphenyl-1H-pyrazol-4-yl)-3-(pyridin-3-yl)-...)
Affinity DataIC50: 2.45E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198136(Ethyl 4-(3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-4-y...)
Affinity DataIC50: 2.56E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198140(5-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-...)
Affinity DataIC50: 2.72E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198137(Ethyl 2-oxo-4-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)...)
Affinity DataIC50: 3.95E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198141(5-(3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-...)
Affinity DataIC50: 4.06E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198138(Ethyl 4-(3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4...)
Affinity DataIC50: 4.28E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198144(5-(3-(3-Nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(...)
Affinity DataIC50: 4.45E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198142(5-(3-(3-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(...)
Affinity DataIC50: 4.57E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198143(5-(3-(4-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(...)
Affinity DataIC50: 7.03E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed