Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50047919
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197156(CHEMBL3930237)
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197164(CHEMBL3921280)
Affinity DataIC50: 116nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197155(CHEMBL3970888)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197162(CHEMBL3984879)
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197163(CHEMBL3956223)
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197156(CHEMBL3930237)
Affinity DataIC50: 135nMAssay Description:Inhibition of HDAC2 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197160(CHEMBL3949111)
Affinity DataIC50: 135nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197159(CHEMBL3914471)
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197158(CHEMBL3947530)
Affinity DataIC50: 142nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197157(CHEMBL3976805)
Affinity DataIC50: 153nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197161(CHEMBL3957732)
Affinity DataIC50: 155nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197156(CHEMBL3930237)
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC1 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged HDAC8 expressed in Escherichia coli DH5alpha (DE3) assessed as inhibition of deacetylation act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
Acharya Nagarjuna University

Curated by ChEMBL
LigandPNGBDBM50197156(CHEMBL3930237)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC3 in human MDA-MB-231 cells assessed as inhibition of deacetylation activity using Fluor-de-Lys as substrate measured after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed