Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50048211
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 22nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 34nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 39nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 39nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 68nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 71nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 76nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 86nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 95nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 117nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 118nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 126nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 144nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 160nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 166nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 269nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 294nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 386nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 400nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 501nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE1A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE10A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE1A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE10A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE11A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE3B using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE2A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE1A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE3B using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE2A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE6C using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE6C using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE11A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE6C using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE10A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208315(CHEMBL3884224)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208311(CHEMBL3885161)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE8A1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE8A1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE8A1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208310(CHEMBL3883753)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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