Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 7578
TargetSerine/threonine-protein kinase WNK1 [166-489](Human)
Novartis Institutes

LigandPNGBDBM203827(WNK463 (2) | WNK463 | N-(tert-butyl)-1-(1-(5-(5-(t...)
Affinity DataIC50: 1nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [1-491](Human)
Novartis Institutes

LigandPNGBDBM203827(WNK463 (2) | WNK463 | N-(tert-butyl)-1-(1-(5-(5-(t...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [1-434](Human)
Novartis Institutes

LigandPNGBDBM203827(WNK463 (2) | WNK463 | N-(tert-butyl)-1-(1-(5-(5-(t...)
Affinity DataIC50: 6nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [1-444](Human)
Novartis Institutes

LigandPNGBDBM203827(WNK463 (2) | WNK463 | N-(tert-butyl)-1-(1-(5-(5-(t...)
Affinity DataIC50: 9nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [1-491](Human)
Novartis Institutes

LigandPNGBDBM203827(WNK463 (2) | WNK463 | N-(tert-butyl)-1-(1-(5-(5-(t...)
Affinity DataIC50: 41nMpH: 7.3 T: 2°CAssay Description:0.2 nM GST-hWNK1(1-491) (Carna Biosciences, cat# 05-179); 3.5 ug/ml GST-OSR1; 20 mM HEPES; 0.01% Tween; 5 mM MnCl2; 1 mM TCEP; 2% DMSO; 0.5 uM ATP, p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase WNK1 [1-491](Human)
Novartis Institutes

LigandPNGBDBM203826((R)-1-(1-(2-(4-methoxyphenyl)acetyl)pyrrolidin-3-y...)
Affinity DataIC50: 856nMpH: 7.3 T: 2°CAssay Description:Each well of the MBP-coated ScintiPlates held 100 ul of a solution containing 20 mM HEPES pH 7.3, 5 mM MnCl2 (WNK1 and WNK4) or 3 mM MnCl2 (WNK2 and ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed