Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50009952
Affinity DataIC50: 150nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 160nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE1 in human H4 cells expressing swedish mutant APP751 assessed as reduction in amyloid beta level measured after 19 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human CYP2C19 preincubated for 10 mins followed by addition of CEC as substrate measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 preincubated for 10 mins followed by addition of BFC as substrate measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 preincubated for 10 mins followed by addition of AMMC as substrate measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 preincubated for 10 mins followed by addition of CEC as substrate measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human CYP2C9 preincubated for 10 mins followed by addition of MFC as substrate measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in HEK293 cells expressing swedish mutant using mcaFRET peptide as substrate measured after 2...More data for this Ligand-Target Pair
