Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018890
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Hepatitis C virus genotype 3a NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50613670(CHEMBL295844)
Affinity DataIC50: 3nMAssay Description:Inhibition of HCV NS4A-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Hepatitis C virus genotype 5a NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50613670(CHEMBL295844)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal HCV NS4A-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 20nMAssay Description:Inhibition of Hepatitis C virus genotype 4a NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 62nMAssay Description:Inhibition of Hepatitis C virus genotype 6a NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50162092(3-Cyclohexyl-1-methyl-2-phenyl-1H-indole-6-carboxy...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 164nMAssay Description:Inhibition of Hepatitis C virus genotype 2b NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50448498(BMS-791325 | Beclabuvir)
Affinity DataIC50: 165nMAssay Description:Inhibition of Hepatitis C virus genotype 2a NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50613671(CHEMBL3126845)
Affinity DataIC50: 440nMAssay Description:Inhibition of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50093011(1-{[(R)-(S)-1-[(S)-2-((S)-2-Acetylamino-2-cyclohex...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of HCV NS4A-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50613672(CHEMBL5269047)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM3879((2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(3S)-3-[(3S)-3-ac...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of HCV NS4A-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50110125(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  3nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50120038(2-{[2-({6-[1-(1-Carboxy-2-phosphono-ethylcarbamoyl...)
Affinity DataKi:  27nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A protease in presence of Zn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50084685(AcAsp-Glu-Dif-Glu-Cha-Cys | 4-(2-Acetylamino-3-car...)
Affinity DataKi:  40nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50103860(2-{[2-(6-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataKi:  200nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50110118(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  700nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50120038(2-{[2-({6-[1-(1-Carboxy-2-phosphono-ethylcarbamoyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Hepatitis C virus NS3/NS4A protease in absence of Zn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed