Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50048108
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204615(CHEMBL3921664)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204639(CHEMBL3894726)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204615(CHEMBL3921664)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204616(CHEMBL3922762)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204616(CHEMBL3922762)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204619(CHEMBL3893810)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204619(CHEMBL3893810)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204620(CHEMBL3950479)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204639(CHEMBL3894726)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204620(CHEMBL3950479)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204618(CHEMBL3934594)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204618(CHEMBL3934594)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204614(CHEMBL3913728)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204614(CHEMBL3913728)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204617(CHEMBL3905284)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204617(CHEMBL3905284)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of ROS1 (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 25nMAssay Description:Inhibition of ALK (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204639(CHEMBL3894726)
Affinity DataIC50: 157nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204615(CHEMBL3921664)
Affinity DataIC50: 220nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204617(CHEMBL3905284)
Affinity DataIC50: 376nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204619(CHEMBL3893810)
Affinity DataIC50: 380nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204614(CHEMBL3913728)
Affinity DataIC50: 393nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204618(CHEMBL3934594)
Affinity DataIC50: 460nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204618(CHEMBL3934594)
Affinity DataIC50: 479nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204615(CHEMBL3921664)
Affinity DataIC50: 570nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204639(CHEMBL3894726)
Affinity DataIC50: 587nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204619(CHEMBL3893810)
Affinity DataIC50: 593nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204617(CHEMBL3905284)
Affinity DataIC50: 601nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204614(CHEMBL3913728)
Affinity DataIC50: 898nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204620(CHEMBL3950479)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204616(CHEMBL3922762)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204616(CHEMBL3922762)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204620(CHEMBL3950479)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed