Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010222
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataEC50:  180nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536418(CHEMBL4591875)
Affinity DataEC50:  190nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536420(CHEMBL4532487)
Affinity DataEC50: >100nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536421(CHEMBL4541575)
Affinity DataEC50:  1.65E+3nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536422(CHEMBL4539707)
Affinity DataEC50:  470nMAssay Description:Inhibition of DHT-induced androgen receptor transactivation in human LNCaP cells after 24 hrs by luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM25458(ABT | CHEMBL254328 | CB 7598 | (1S,2R,5S,10R,11S,1...)
Affinity DataIC50: 48nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50435990(VN/124 | VN/124-1 | TOK-001 | GALETERONE | US96112...)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536418(CHEMBL4591875)
Affinity DataIC50: 480nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536421(CHEMBL4541575)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536423(CHEMBL4528465)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536419(CHEMBL4552506)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50536424(CHEMBL4521939)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of CYP17 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed