Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50010020
TargetCytochrome P450 1A2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DHFR using folic aid as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50534415(CHEMBL4464764)
Affinity DataIC50: 9.93E+4nMAssay Description:Inhibition of human ERG in membranes incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed