Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50010017
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 14nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 96nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 107nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534411(CHEMBL4578033)
Affinity DataIC50: 443nMAssay Description:Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 495nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534411(CHEMBL4578033)
Affinity DataIC50: 763nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 803nMAssay Description:Inhibition of human BuChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 5.91E+3nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of human AChE using ACTI as substrate incubated for 40 mins measured at 1 min intervals for 10 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534413(CHEMBL4451368)
Affinity DataIC50: 9.72E+3nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534412(CHEMBL4545740)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534410(CHEMBL4520824)
Affinity DataIC50: 4.68E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50534414(CHEMBL4452331)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of equine BuChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM11682(2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethyl...)
Affinity DataIC50: 7.42E+4nMAssay Description:Inhibition of electric eel AChE using ACTI as substrate preincubated for 29 mins followed by substrate addition measured at 1 min intervals for 10 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed