Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50048084
TargetCholinesterase(Horse)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 61nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 610nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204090(CHEMBL3958859)
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204087(CHEMBL3920392)
Affinity DataIC50: 7.88E+3nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204091(CHEMBL3922437)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204088(CHEMBL3907011)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204091(CHEMBL3922437)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204086(CHEMBL238756 | Avarol-3''-Thiosalicylate)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204086(CHEMBL238756 | Avarol-3''-Thiosalicylate)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204089(CHEMBL3945723)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Horse)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204090(CHEMBL3958859)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50242257(2-(1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8,8a-octahydr...)
Affinity DataIC50: 2.86E+5nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate incubated for 15 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204090(CHEMBL3958859)
Affinity DataKi:  0.000590nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204086(CHEMBL238756 | Avarol-3''-Thiosalicylate)
Affinity DataKi:  0.0585nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Istituto Di Chimica Biomolecolare (Icb)

Curated by ChEMBL
LigandPNGBDBM50204087(CHEMBL3920392)
Affinity DataKi:  0.221nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed