Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 50047765
Affinity DataEC50: 248nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 211nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 144nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 199nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 188nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 399nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 222nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataEC50: 151nMAssay Description:Inhibition of HDAC6 in human A2780S cells assessed as tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system incubated for 1 hr by kinase-g...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant HDAC1 (482 residues) by Color-de-Lys assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length C-terminal His/FLAG-tagged human recombinant HDAC1 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length C-terminal His-tagged human recombinant HDAC3/NCOR2 (395 to 489 residues) expressed in baculovirus infected insect Sf9 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant HDAC10 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as release of AM...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Ac-Leu-Gly-Lys (Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in baculovirus infected insect Sf9 cells using Ac-peptide-AMC as substrate assessed as re...More data for this Ligand-Target Pair
