Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50047404
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guinea pig brain homogenate incubated for 120 mins by solid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B expressed in mouse L(tk-) cell membranes incubated for 120 mins by microbeta scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50079387(CHEMBL28564 | 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-b...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B expressed in mouse L(tk-) cell membranes incubated for 120 mins by microbeta scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50204884(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Affinity DataKi:  30nMAssay Description:Binding affinity to GluN2B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50009307(Di-o-tolylguanidine | DITOLYLGUANIDINE)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guinea pig brain homogenate incubated for 120 mins by solid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guinea pig brain homogenate incubated for 120 mins by solid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50165202(CHEMBL3797704)
Affinity DataKi:  697nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B expressed in mouse L(tk-) cell membranes incubated for 120 mins by microbeta scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50165202(CHEMBL3797704)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guinea pig brain homogenate incubated for 120 mins by solid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed