Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50047466
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169057(CHEMBL3805896)
Affinity DataEC50:  0.260nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169061(CHEMBL3805393)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169060(CHEMBL3804939)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169059(CHEMBL3805627)
Affinity DataEC50:  48nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169058(CHEMBL3806049)
Affinity DataEC50:  21nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169056(CHEMBL3806163)
Affinity DataEC50:  0.220nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169061(CHEMBL3805393)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169056(CHEMBL3806163)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169057(CHEMBL3805896)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169057(CHEMBL3805896)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169060(CHEMBL3804939)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169056(CHEMBL3806163)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169061(CHEMBL3805393)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169058(CHEMBL3806049)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169060(CHEMBL3804939)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169058(CHEMBL3806049)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169059(CHEMBL3805627)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169059(CHEMBL3805627)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169059(CHEMBL3805627)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169057(CHEMBL3805896)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169061(CHEMBL3805393)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169058(CHEMBL3806049)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169060(CHEMBL3804939)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed