Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50018878
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613572(CHEMBL5275121)
Affinity DataEC50:  68nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613573(CHEMBL5286406)
Affinity DataEC50:  47nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613574(CHEMBL5273781)
Affinity DataEC50:  63nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613575(CHEMBL5289884)
Affinity DataEC50:  26nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50397965(CHEMBL2180789)
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50613581(CHEMBL5286395)
Affinity DataIC50: 0.0630nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50613582(CHEMBL5288570)
Affinity DataIC50: 0.102nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM239755(US9394311, 38 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM239754(US9394311, 37)
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
LigandPNGBDBM50613580(CHEMBL5268187)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full-length recombinant human PDE10A by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHormone-sensitive lipase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613578(CHEMBL5280062)
Affinity DataIC50: 20nMAssay Description:Inhibition of human HSLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHormone-sensitive lipase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613577(CHEMBL5291436)
Affinity DataIC50: 30nMAssay Description:Inhibition of human HSLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHormone-sensitive lipase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613576(CHEMBL5275875)
Affinity DataIC50: 300nMAssay Description:Inhibition of human HSLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHormone-sensitive lipase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613579(CHEMBL5290812)
Affinity DataIC50: 570nMAssay Description:Inhibition of human HSLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197092(CHEMBL3947458)
Affinity DataKi:  12nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197094(CHEMBL3941588)
Affinity DataKi:  22nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613583(CHEMBL5287034)
Affinity DataKi:  30nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197091(CHEMBL1738980)
Affinity DataKi:  90nMAssay Description:Inhibition of FABP3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197091(CHEMBL1738980)
Affinity DataKi:  100nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613583(CHEMBL5287034)
Affinity DataKi:  150nMAssay Description:Inhibition of FABP3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197092(CHEMBL3947458)
Affinity DataKi:  380nMAssay Description:Inhibition of FABP3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197094(CHEMBL3941588)
Affinity DataKi:  490nMAssay Description:Inhibition of FABP5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197092(CHEMBL3947458)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of FABP5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50613583(CHEMBL5287034)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of FABP5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197094(CHEMBL3941588)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of FABP3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50197091(CHEMBL1738980)
Affinity DataKi: >2.30E+4nMAssay Description:Inhibition of FABP5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed