Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50047113
TargetSerine/threonine-protein kinase SIK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 9nMAssay Description:Inhibition of human SIK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant KHS1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MST4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 25(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant YSK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant MST3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148927(CHEMBL3770588)
Affinity DataIC50: 45nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148918(CHEMBL3769552)
Affinity DataIC50: 53nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148920(CHEMBL3769478)
Affinity DataIC50: 57nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 69nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148919(CHEMBL3770363)
Affinity DataIC50: 73nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148928(CHEMBL3770909)
Affinity DataIC50: 124nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148930(CHEMBL3769748)
Affinity DataIC50: 145nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148929(CHEMBL3770369)
Affinity DataIC50: 147nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148922(CHEMBL3770295)
Affinity DataIC50: 148nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148931(CHEMBL3770186)
Affinity DataIC50: 222nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148926(CHEMBL3769456)
Affinity DataIC50: 341nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148923(CHEMBL3770943)
Affinity DataIC50: 399nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148924(CHEMBL3769981)
Affinity DataIC50: 813nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148925(CHEMBL3770806)
Affinity DataIC50: 980nMAssay Description:Inhibition of PAK1 in human EBC1 cells assessed as reduction in levels of MEK phosphorylation at S298 residue after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148928(CHEMBL3770909)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148920(CHEMBL3769478)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148927(CHEMBL3770588)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148919(CHEMBL3770363)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148930(CHEMBL3769748)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148929(CHEMBL3770369)
Affinity DataKi:  6.10nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148926(CHEMBL3769456)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148918(CHEMBL3769552)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148922(CHEMBL3770295)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148923(CHEMBL3770943)
Affinity DataKi:  19nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148931(CHEMBL3770186)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148925(CHEMBL3770806)
Affinity DataKi:  64nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50148924(CHEMBL3769981)
Affinity DataKi:  66nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed