Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50046887
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM14 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50:  100nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM13 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MV4-11 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MOLM14 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 mediated Stat5 phosphorylation in human MOLM13 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataEC50: <30nMAssay Description:Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MV4-11 cells for 4 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50: 40nMAssay Description:Inhibition of wild-type FLT3 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50: 421nMAssay Description:Inhibition of BTK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135187(CHEMBL3745919 | US10266535, Compound 22)
Affinity DataIC50: 559nMAssay Description:Inhibition of c-KIT (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed