Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50046727
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 190nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)
Affinity DataIC50: 560nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50: 580nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)
Affinity DataIC50: 1.31E+3nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128342(CHEMBL3629175)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128343(CHEMBL3629176)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50128344(CHEMBL3629177)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of 5-LO in mouse BMM cells assessed as formation of LTC4 after 30 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetTumor necrosis factor ligand superfamily member 11(Mouse)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Antiosteoclast activity in mouse BMM cells assessed as reduction of RANKL-induced osteoclasts differentiation by measuring TRAP positive multinucleat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed