Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50046596
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120847(CHEMBL3618487)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120845(CHEMBL3618485)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM32252(BAS_01057772 | 2-(1-benzimidazolyl)-1-(5-ethyl-2,4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120834(CHEMBL2011396)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120835(CHEMBL2011401)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120832(CHEMBL3618483)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120831(CHEMBL3618482)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50293578(4-(2-(4-Hydroxyphenylamino)thiazol-4-yl)benzene-1,...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50293573(CHEMBL239103 | cid_2175556 | 4-(4-(2,4-dihydroxyph...)
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120823(CHEMBL1904421)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120836(CHEMBL572150)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120846(CHEMBL3618486)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120824(CHEMBL3618478)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120826(CHEMBL1510984)
Affinity DataIC50: 3.30E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120830(CHEMBL599385)
Affinity DataIC50: 4.23E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50293577(cid_972292 | CHEMBL563294 | 4-(4-(4-Hydroxyphenyl)...)
Affinity DataIC50: 4.92E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120829(CHEMBL596726)
Affinity DataIC50: 6.42E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120828(CHEMBL590969)
Affinity DataIC50: 6.80E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120837(CHEMBL3618484)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50051863(CHEMBL1081479)
Affinity DataIC50: 7.35E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120827(CHEMBL3618481)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50312869(N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...)
Affinity DataIC50: 1.04E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50293576(CHEMBL562493 | 4131JH0380 | 4-(4-phenylthiazol-2-y...)
Affinity DataIC50: 1.27E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.40E+6nMAssay Description:Inhibition of human salivary alpha-amylase using rice starch as substrate after 12 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50161650(4-(benzo[d][1,3]dioxol-5-yl)-3-(5-ethyl-2,4-dihydr...)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120833(CHEMBL600247)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120825(CHEMBL3618480)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120854(CHEMBL3618493)
Affinity DataKi:  8nMAssay Description:Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120851(CHEMBL1233515)
Affinity DataKi:  12nMAssay Description:Inhibition of human pancreatic alpha-amylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120850(CHEMBL3618491)
Affinity DataKi:  12nMAssay Description:Inhibition of human pancreatic alpha-amylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120843(CHEMBL3616594)
Affinity DataKi:  14nMAssay Description:Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120842(CHEMBL3618489)
Affinity DataKi:  15nMAssay Description:Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120844(CHEMBL3616595)
Affinity DataKi:  42nMAssay Description:Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120852(CHEMBL1230193)
Affinity DataKi:  75nMAssay Description:Inhibition of human pancreatic alpha-amylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120853(CHEMBL3618492)
Affinity DataKi:  190nMAssay Description:Non-competitive inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120849(CHEMBL3618490)
Affinity DataKi:  700nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120848(CHEMBL3618488)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of human pancreatic alpha-amylase expressed in Pichia pastoris using amylase as substrate preincubated with substrate for 10 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-amylase 1A(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-bet...)
Affinity DataKi:  2.60E+3nMAssay Description:Non-competitive inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120855(CHEMBL3618494)
Affinity DataKi:  3.60E+3nMAssay Description:Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120856(CHEMBL3618495)
Affinity DataKi:  6.10E+3nMAssay Description:Competitive inhibition of human pancreatic alpha-amylase by double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120839(CHEMBL1234040)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM29143(Chalcone, 13 | CHEMBL7976 | cid_637760 | Chalcone ...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using soluble starch as substrate after 30 mins by Bernfeld methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120841(CHEMBL3616593)
Affinity DataKi: <1.00E+7nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using DP17 amylose as substrate preincubated for 5 mins followed by substrate addition by copper-bicin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-amylase type A isozyme(Barley)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120841(CHEMBL3616593)
Affinity DataKi: <1.00E+7nMAssay Description:Inhibition of recombinant barley alpha-amylase isozyme-1 using DP17 amylose as substrate preincubated for 5 mins followed by substrate addition by co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120840(CHEMBL1213470)
Affinity DataKi:  1.80E+7nMAssay Description:Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic alpha-amylase(Human)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50120838(CHEMBL1233953)
Affinity DataKi:  1.80E+6nMAssay Description:Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed