Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50046590
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065611(CHEMBL3401383)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [33P]S1P from human S1P2 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120582(CHEMBL3618199)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065611(CHEMBL3401383)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120583(CHEMBL3618200)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120579(CHEMBL3618196)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120581(CHEMBL3618198)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120580(CHEMBL3618197)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120583(CHEMBL3618200)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120582(CHEMBL3618199)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065611(CHEMBL3401383)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120513(CHEMBL3618189)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120580(CHEMBL3618197)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120579(CHEMBL3618196)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120581(CHEMBL3618198)
Affinity DataIC50: 123nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 430nMAssay Description:Displacement of [33P]S1P from human S1P2 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Rat)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120514(CHEMBL3618190)
Affinity DataIC50: 690nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120574(CHEMBL3618191)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120513(CHEMBL3618189)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120514(CHEMBL3618190)
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120575(CHEMBL3618192)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120576(CHEMBL3618193)
Affinity DataIC50: 9.50E+3nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P1 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P4 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P3 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM149705(US8975409, Example 9(3))
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P5 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120577(CHEMBL3618194)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50120578(CHEMBL3618195)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed