Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50046712
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127334(CHEMBL3628065)
Affinity DataIC50: 80nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127381(CHEMBL3628067)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127382(CHEMBL3628183)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127380(CHEMBL3628066)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127274(CHEMBL3628053)
Affinity DataIC50: 280nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127275(CHEMBL3628054)
Affinity DataIC50: 340nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127393(CHEMBL3628185)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127389(CHEMBL3628184)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127399(CHEMBL3628186)
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127399(CHEMBL3628186)
Affinity DataIC50: 650nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127382(CHEMBL3628183)
Affinity DataIC50: 710nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127393(CHEMBL3628185)
Affinity DataIC50: 720nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127389(CHEMBL3628184)
Affinity DataIC50: 860nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127381(CHEMBL3628067)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127334(CHEMBL3628065)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127380(CHEMBL3628066)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127290(CHEMBL3628059)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127276(CHEMBL3628055)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127277(CHEMBL3628056)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127293(CHEMBL3628062)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127289(CHEMBL3628058)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127294(CHEMBL3628063)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127288(CHEMBL3628057)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127277(CHEMBL3628056)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127276(CHEMBL3628055)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127289(CHEMBL3628058)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127295(CHEMBL3628064)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127288(CHEMBL3628057)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127291(CHEMBL3628060)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127290(CHEMBL3628059)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127293(CHEMBL3628062)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127295(CHEMBL3628064)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127294(CHEMBL3628063)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127291(CHEMBL3628060)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127292(CHEMBL3628061)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127275(CHEMBL3628054)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
1St Affiliated Hospital of Guangxi Medical University

Curated by ChEMBL
LigandPNGBDBM50127274(CHEMBL3628053)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed