Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50046634
LigandPNGBDBM50122453(CHEMBL3622491)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50122451(CHEMBL3622492)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122449(CHEMBL3622483)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50122484(CHEMBL3622484)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50122485(CHEMBL3622482)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50122452(CHEMBL3622490)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122486(CHEMBL3622481)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50122546(CHEMBL3622507)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122489(CHEMBL3622478)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122487(CHEMBL3622480)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122455(CHEMBL3622488)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122450(CHEMBL3622493)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122525(CHEMBL3622503)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122528(CHEMBL3622504)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122458(CHEMBL3622485)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122454(CHEMBL3622489)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122496(CHEMBL3622497)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122457(CHEMBL3622486)
Affinity DataIC50: 163nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122488(CHEMBL3622479)
Affinity DataIC50: 181nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122456(CHEMBL3622487)
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122494(CHEMBL3622495)
Affinity DataIC50: 333nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122493(CHEMBL3622494)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122498(CHEMBL3622499)
Affinity DataIC50: 518nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122552(CHEMBL3622508)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122537(CHEMBL3622505)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122501(CHEMBL3622502)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122499(CHEMBL3622500)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122555(CHEMBL3622509)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122495(CHEMBL3622496)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122490(CHEMBL3622477)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122545(CHEMBL3622506)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122500(CHEMBL3622501)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122497(CHEMBL3622498)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122449(CHEMBL3622483)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant TACE using Mca-PLAQAV-Dpa-RSSSR-NH2 as substrate preincubated for 15 mins measured every 30 secs for 30 mins by fluor...More data for this Ligand-Target Pair
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PubMed
TargetCollagenase 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122449(CHEMBL3622483)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MMP13 using 5-FAMTPGPLGL[Dap(DNP)]ARRK(5-TAMRA)-amide as substrate after 45 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122449(CHEMBL3622483)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ADAMTS13 using FRETSVWF73 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50122449(CHEMBL3622483)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAMTS5 (unknown origin) using WAAG-3R as substrate preincubated for 15 mins followed by substrate addition measured every 30 secs for ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed