Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50046456
TargetTryptase beta-2/delta/gamma(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of tryptase (unknown origin) using t-Boc-Phe-Ser-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of thrombin (unknown origin) using t-Boc-Val-Pro-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2016
Entry Details Article
PubMed