Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50046606
Affinity DataKd: 21nMAssay Description:Binding affinity to human CBP by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 32nMAssay Description:Binding affinity to human p300 by ITC analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human Vps34 by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of GRP94 (unknown origin) expressed in HEK293 cells assessed as reduction of Toll-like receptor trafficking to cell membrane treated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of JAK3 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC3 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acid residues) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of JAK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acid residues) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of JAK1 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human MAO-B using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.62E+3nMAssay Description:Inhibition of TYK2 (unknown origin) after 20 mins by radiometric analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human MAO-A using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kalpha by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human mTOR by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kdelta by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kgamma by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PI3Kbeta by TR-FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acid residues) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC5 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC5 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC6 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC6 in human HeLa nuclear extracts by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of human MAO-A using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of human MAO-A using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human MAO-B using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human MAO-B using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
