Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50046046
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataIC50: 840nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataIC50: 1.20E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataIC50: 1.50E+4nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50042876([2,2']Bipyridinyl-5,5'-dicarboxylic acid | CHEMBL3...)
Affinity DataKi:  140nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50092609(CHEMBL3586252)
Affinity DataKi:  200nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine-2,5-dicarboxylic acid | pyr...)
Affinity DataKi:  2.60E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed