Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50045888
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  1.13E+4nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  1.37E+4nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  2.32E+4nMAssay Description:Agonist activity at rat mGluR1 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  2.15E+4nMAssay Description:Agonist activity at rat mGluR8 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGluR7 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  8.22E+4nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  1.26E+4nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  1.83E+4nMAssay Description:Agonist activity at rat mGluR2 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  100nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  300nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  1.25E+3nMAssay Description:Agonist activity at rat mGluR8 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGluR7 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  6.01E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50:  300nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50088290(CHEMBL3427499)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGluR2 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50217031((1S,2R)-1-amino-2-phosphonomethylcyclopropane-carb...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat mGluR8 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 7(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  4.26E+5nMAssay Description:Agonist activity at rat mGluR7 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Univ. Rouen

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at rat mGluR6 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed