Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50045566
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068283(CHEMBL3403371)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068285(CHEMBL3403372)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068277(CHEMBL3403358)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068261(CHEMBL3403361)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068256(CHEMBL3403367)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068282(CHEMBL3403360)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068254(CHEMBL3403365)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068262(CHEMBL3403362)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068260(CHEMBL3403370)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068259(CHEMBL3403369)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068281(CHEMBL3403359)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068257(CHEMBL3403368)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068255(CHEMBL3403366)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 46nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50: 140nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068253(CHEMBL3403364)
Affinity DataIC50: 170nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068263(CHEMBL3403363)
Affinity DataIC50: 190nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068282(CHEMBL3403360)
Affinity DataIC50: 200nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068285(CHEMBL3403372)
Affinity DataIC50: 200nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068272(CHEMBL3403353)
Affinity DataIC50: 300nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068266(CHEMBL3403349)
Affinity DataIC50: 370nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068283(CHEMBL3403371)
Affinity DataIC50: 380nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068261(CHEMBL3403361)
Affinity DataIC50: 420nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068273(CHEMBL3403354)
Affinity DataIC50: 430nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068254(CHEMBL3403365)
Affinity DataIC50: 440nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068277(CHEMBL3403358)
Affinity DataIC50: 520nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068281(CHEMBL3403359)
Affinity DataIC50: 550nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068256(CHEMBL3403367)
Affinity DataIC50: 560nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068262(CHEMBL3403362)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068276(CHEMBL3403357)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068265(CHEMBL3403348)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068259(CHEMBL3403369)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068269(CHEMBL3403351)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068255(CHEMBL3403366)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068257(CHEMBL3403368)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068275(CHEMBL3403356)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068287(CHEMBL3403346)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068260(CHEMBL3403370)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068274(CHEMBL3403355)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068271(CHEMBL3403352)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068264(CHEMBL3403347)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068285(CHEMBL3403372)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068285(CHEMBL3403372)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50068268(CHEMBL3403350)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068272(CHEMBL3403353)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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