Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50045539
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 90nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 240nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 270nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 530nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87576(SMR000658847 | MLS001100779 | cid_24793407 | N-[(3...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87575(N-[(4,5-dimethyl-1,3-thiazol-2-yl)methyl]-4-methox...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 760nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 910nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067199(CHEMBL3187862)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067208(CHEMBL3303292)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87569(N-(1-phenylethyl)-4-{[1-(pyridin-2-ylmethyl)piperi...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067205(CHEMBL3183447)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067210(CHEMBL3303803)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067204(CHEMBL3183383)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067205(CHEMBL3183447)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067201(CHEMBL3186365)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87574(cid_24793028 | MLS001082585 | N-[2-(cyclohexen-1-y...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87572(N-(2,3-dihydro-1H-inden-1-yl)-4-methoxy-3-[(1-prop...)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067199(CHEMBL3187862)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87578(SMR000664527 | MLS001101393 | N-(2-phenylethyl)-3-...)
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87577(4-methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxy-N-(1-...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067208(CHEMBL3303292)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067210(CHEMBL3303803)
Affinity DataIC50: 6.12E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067201(CHEMBL3186365)
Affinity DataIC50: 8.09E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067204(CHEMBL3183383)
Affinity DataIC50: 9.27E+3nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067209(CHEMBL3303792)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067207(CHEMBL3304438)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067206(CHEMBL3188567)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067203(CHEMBL3182315)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067202(CHEMBL1872483)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50067200(CHEMBL3187348)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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